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Fig. 3 | Journal of the Egyptian National Cancer Institute

Fig. 3

From: High-grade transformation of adenoid cystic carcinoma of parotid gland with isolated intratemporal facial nerve involvement: a case report and literature review

Fig. 3

Histopathological examination and immunohistochemistry studies of the tumor. The tubular and cribiform pattern of conventional ACC (thin arrow) with a transition to a solid high grade carcinoma (thick arrow) A) H&E x100, B) H&E x400. C) Tumour infiltrating a nerve (thick arrow) H&E x100. Ki67 labelling index was D) 70% in High grade component. Smooth muscle actin (SMA) showed E) Loss of expression in high grade component. p53 was F) strongly positive in the high grade components (thin arrow) and weakly positive/negative in the low grade components (thick arrow)

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