Table 2 Statistical analysis of studied biomarkers in breast cancer patients

PTGS2 (ng/ml)

 Range

1.07–2.89

1.53–40.0

1.38–45.0

 Mean ± SD

2.27 ± 0.42

4.52 ± 2.06

5.68 ± 2.32

 P1

0.002*

 < 0.001*

 P2

0.031*

MDA (nmol/ml)

 Range

0.26–2.50

5.87–14.65

1.0–28.27

 Mean ± SD

1.19 ± 0.66

6.65 ± 4.14

9.29 ± 6.26

 P1

 < 0.001*

 < 0.001*

 P2

0.026*

GSH (mmole/L)

 Range

7.14–10.80

6.30–10.60

5.60–9.41

 Mean ± SD

8.98 ± 0.88

8.49 ± 0.95

7.85 ± 0.96

 P1

0.293

 < 0.001*

 P2

 < 0.001*

Ferroportin (ng/ml)

 Range

2.01–4.75

2.05–7.15

2.01–3.98

 Mean ± SD

2.56 ± 0.59

3.48 ± 1.55

2.58 ± 0.99

 P1

0.014*

0.740

 P2

 < 0.001^*

Hb (g/dl)

 Range

12.5 – 14.5

9.50–13.8

9.15–12.40

 Mean ± SD

13.10 ± 2.81

11.40 ± 1.27

10.60 ± 0.89

 P1

0.002*

 < 0.001^*

 P2

0.149

Iron (µg/dl)

 Range

29.0–106.0

22.0–113.0

33.0–111.0

 Mean ± SD

61.73 ± 19.84

55.33 ± 19.45

66.64 ± 19.90

 P1

0.177

0.305

 P2

 < 0.001*

Ferritin (ng/ml)

 Range

8.30–86.3

6.10 – 140

8.70–97.9

 Mean ± SD

40.99 ± 15.10

80.82 ± 22.0

59.91 ± 16.49

 P1

0.028*

0.332

 P2

 < 0.001*

Transferrin saturation (%)

 Range

5.74–37.60

5.54–32.03

8.27–33.50

 Mean ± SD

18.54 ± 5.59

16.75 ± 5.85

19.59 ± 6.44

 P1

0.197

0.476

 P2

 < 0.001*

UIBC (µg/dl)

 Range

161.0–476.0

174.0–397.0

200.0–380.0

 Mean ± SD

264.5 ± 60.88

281.0 ± 53.45

278.1 ± 48.43

 P1

0.226

0.293

 P2

0.582

TIBC (µg/dl)

 Range

240.0–515.0

233.0–469.0

229.0–448.0

 Mean ± SD

319.1 ± 68.84

336.4 ± 52.25

328.2 ± 48.23

 P1

0.231

0.514

 P2

0.099