Table 1 The network hub genes. DEGs were sorted based on the highest degree. Status column exhibits whether a gene is upregulated or downregulated in the analysis
De genes | Degree | Betweenness | Status |
|---|---|---|---|
cdk1 | 102 | 6366.23 | Up |
CCNB1 | 94 | 324.32 | Up |
CCNA2 | 93 | 476.87 | Up |
CDC20 | 89 | 1735.14 | Up |
PBK | 87 | 2489.09 | Up |
CHEK1 | 80 | 1230.53 | Up |
ZWINT | 79 | 2548.27 | Up |
CDKN3 | 72 | 1791.96 | Up |
HIST1H2BB | 25 | 747.8 | Up |
HIST1H2BM | 25 | 747.8 | Up |
COL1A2 | 21 | 2108.26 | Up |
COL1A1 | 19 | 1422 | Up |
COL3A1 | 18 | 1345.35 | Up |
CXCL1 | 18 | 4174.93 | Up |
ORM2 | 15 | 3172.16 | Down |
EPHB2 | 14 | 2414.36 | Up |
AGT | 14 | 1555.01 | Up |
FGA | 12 | 1101.23 | Down |
SPARC | 12 | 4279.68 | Up |
GSTA1 | 12 | 2290.52 | Up |
GSTA3 | 12 | 2290.52 | Down |
ITGA2 | 11 | 2797.82 | Up |
HGF | 11 | 6349.3 | Down |
ZBTB16 | 7 | 3430.08 | Down |
RCN1 | 5 | 2436.24 | Up |
CFTR | 5 | 3687.92 | Up |