Journal of the Egyptian National Cancer Institute

Table 3 The diagnostic validity and the optimal cut-off values of different gene expressions and AFP as markers for HCC

From: Noninvasive identification of molecular biomarkers of hepatocellular carcinoma in HCV-Egyptian patients

Variable	Cutoff	Sens. %	Spec.%	AUC	SE	95% (CI)	p-value
AFP	7.55	78.6%	72.7%	0.799	0.08	0.64–0.95	0.003
CK-1	0.872	71.4%	59.1%	0.65	0.10	0.46–0.84	0.14
GPC-3	1.23	64.3	63.4%	0.67	0.10	0.47–0.87	0.10
ADAM-8	0.575	85.7%	59.1%	0.70	0.09	0.52–0.87	0.05
HGF	2.30	71.4%	54.5%	0.66	0.10	0.45–0.87	0.11
MDK	1.93	50%	68.2%	0.56	0.11	0.34–0.78	0.55

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