Total no. | No. of events | Cumulative survival estimate at 5 years (%) | p-value | |
---|---|---|---|---|
Whole group | 119 | 50 | 0.564 | - |
Age (years) | ||||
< 52 | 61 | 22 | 0.679 | 0.036 |
≥ 52 | 58 | 28 | 0.435 | |
Curative surgery type | ||||
MRM | 80 | 33 | 0.562 | 0.577 |
BCS | 39 | 17 | 0.580 | |
Maximum tumor diameter (cm) | ||||
< 4 | 65 | 24 | 0.630 | 0.037 |
≥ 4 | 54 | 26 | 0.502 | |
pT stage | ||||
Stages 1 & 2 | 70 | 23 | 0.678 | < 0.001 |
Stages 3 & 4 | 49 | 27 | 0.407 | |
pN status | ||||
Negative | 68 | 24 | 0.634 | 0.023 |
Positive | 51 | 26 | 0.460 | |
Capsular invasion (n = 51) | ||||
Absent | 17 | 6 | 0.589 | 0.220 |
Present | 34 | 20 | 0.410 | |
LVI (n = 117) | ||||
Absent | 73 | 26 | 0.605 | 0.012 |
Present | 44 | 23 | 0.520 | |
Grade | ||||
II | 20 | 8 | 0.610 | 0.627 |
III | 99 | 42 | 0.558 | |
Initial TNM stage | ||||
Stages I & II | 71 | 24 | 0.659 | 0.001 |
Stage III | 47 | 26 | 0.414 | |
Pathological subtype | ||||
Spindle cell carcinoma | 8 | 5 | 0.286 | 0.032 |
Others | 111 | 45 | 0.582 | |
Pathological subtype | ||||
Squamous cell carcinoma | 89 | 36 | 0.561 | 0.853 |
Others | 30 | 14 | 0.584 | |
Ki-67 % | ||||
< 45 | 58 | 16 | 0.736 | < 0.001 |
≥ 45 | 55 | 34 | 0.359 | |
Molecular subtype | ||||
TN | 77 | 37 | 0.501 | 0.016 |
Non-TN | 42 | 13 | 0.675 | |
NACT receipt | ||||
Not received | 78 | 31 | 0.632 | 0.015 |
Received | 41 | 19 | 0.395 | |
NACT type (n = 41) | ||||
Anthracycline/taxanes | 27 | 10 | 0.474 | 0.119 |
Others | 14 | 9 | 0.256 | |
Response to NACT (n = 40) | ||||
RCB 0 & I | 6 | 2 | NA | 0.079 |
RCBII & III | 34 | 3 | 0.725 | |
ACT receipt | ||||
Not received | 39 | 25 | 0.307 | < 0.001 |
Received | 80 | 25 | 0.693 | |
ACT type (n = 80) | ||||
Anthracycline only | 20 | 7 | 0.820 | 0.007 |
Anthracycline & taxanes | 40 | 10 | 0.734 | |
Others | 20 | 9 | NA | |
Start of ACT (days) | ||||
≤ 30 | 41 | 10 | 0.766 | 0.186 |
> 30 | 39 | 15 | 0.603 | |
PORT | ||||
No | 25 | 13 | 0.563 | 0.642 |
Yes | 94 | 37 | 0.564 |