Total no. | No. of events | Cumulative survival estimate at 5 years (%) | p-value | |
---|---|---|---|---|
Whole cohort | 135 | 49 | 0.576 | - |
Age (years) | ||||
< 52 | 66 | 18 | 0.669 | 0.011 |
≥ 52 | 69 | 31 | 0.478 | |
Surgery type (n = 125) | ||||
MRM | 80 | 27 | 0.575 | < 0.001 |
BCS | 39 | 9 | 0.734 | |
Palliative mastectomy | 6 | 5 | NA | |
Maximum tumor diameter (cm) (n = 125) | ||||
< 4 | 65 | 14 | 0.740 | < 0.001 |
≥ 4 | 60 | 27 | 0.445 | |
pT stage (n = 125) | ||||
Stages 1 & 2 | 70 | 14 | 0.741 | < 0.001 |
Stages 3 & 4 | 55 | 27 | 0.436 | |
pN status (n = 119) | ||||
Negative | 68 | 13 | 0.735 | 0.001 |
Positive | 51 | 24 | 0.485 | |
Capsular invasion (n = 51) | ||||
Absent | 17 | 6 | 0.676 | 0.186 |
Present | 34 | 18 | 0.403 | |
LVI (n = 133) | ||||
Absent | 74 | 17 | 0.700 | < 0.001 |
Present | 59 | 31 | 0.413 | |
Grade | ||||
II | 22 | 6 | 0.693 | 0.279 |
III | 113 | 43 | 0.549 | |
Initial TNM stage (n = 129) | ||||
Stages I &II | 71 | 0 | 0.718 | < 0.001 |
Stage III | 47 | 21 | 0.508 | |
Stage IV | 11 | 8 | 0.182 | |
Pathological subtype | ||||
Spindle cell carcinoma | 10 | 6 | 0.281 | 0.036 |
Others | 125 | 43 | 0.600 | |
Pathological subtype | ||||
Squamous cell carcinoma | 101 | 38 | 0.541 | |
Others | 34 | 11 | 0.666 | 0.263 |
Ki-67% (n = 129) | ||||
< 45 | 64 | 14 | 0.730 | < 0.001 |
≥ 45 | 65 | 35 | 0.423 | |
Molecular subtype | ||||
TN | 89 | 37 | 0.517 | 0.029 |
Non-TN | 46 | 12 | 0.697 | |
NACT receipt | ||||
Not received | 81 | 21 | 0.601 | 0.027 |
Received | 41 | 18 | 0.513 | |
NACT type (N = 41) | ||||
Anthracycline & taxanes | 27 | 9 | 0.577 | 0.268 |
Others | 14 | 9 | 0.408 | |
Response to NACT (n = 40) | ||||
RCB-0 & I | 6 | 1 | 0.750 | 0.286 |
RCB-II & III | 34 | 16 | 0.487 | |
ACT receipt | ||||
Not received | 40 | 17 | 0.480 | 0.019 |
Received | 80 | 20 | 0.699 | |
ACT type (n = 80) | ||||
Anthracycline | 20 | 2 | 0.868 | 0.011 |
Anthracycline & taxanes | 40 | 9 | 0.686 | |
Others | 20 | 9 | 0.533 | |
ACT start (days) (n = 80) | ||||
≤ 30 days | 41 | 9 | 0.739 | 0.716 |
> 30 days | 39 | 10 | 0.670 | |
PORT (n = 119) | ||||
No | 25 | 10 | 0.578 | 0.253 |
Yes | 94 | 26 | 0.648 |