Table 3 Event-free survival and its relation to different prognostic factors
Factors | EFS% | Median (months) | p-value | ||||
|---|---|---|---|---|---|---|---|
n | 6 m | 1 yr | 2 yrs | 3 yrs | (95% CI) | ||
All | 69 | 94.0 | 90.7 | 88.8 | 83.6 | NA | NA |
Gender | |||||||
Male | 57 | 96.4 | 92.5 | 90.3 | 83.8 | NA | 0.413 |
Female | 12 | 81.8 | 81.8 | 81.8 | 81.8 | NA | |
Age groups | |||||||
0–5 yrs | 13 | 92.3 | 92.3 | 92.3 | 92.3 | NA | 0.178 |
> 5–10 yrs | 29 | 96.4 | 92.4 | 92.4 | 92.4 | NA | |
> 10–15 yrs | 21 | 95.2 | 95.2 | 89.9 | 80.0 | NA | |
≥ 15 yrs | 6 | 80 | 53.3 | 53.3 | 53.3 | NA | |
ESR | |||||||
< 30 | 44 | 92.9 | 90.3 | 87.4 | 87.4 | NA | 0.997 |
≥ 30 | 25 | 96.0 | 90.4 | 90.4 | 76.2 | NA | |
LN no | |||||||
< 3 | 40 | 100 | 100 | 96.9 | 96.9 | NA | 0.005 |
≥ 3 | 29 | 85.2 | 76.4 | 76.4 | 68.8 | NA | |
Extra nodal | |||||||
No | 37 | 100 | 100 | 96.6 | 96.6 | NA | 0.013 |
Yes | 32 | 87.1 | 79.5 | 79.5 | 70.7 | NA | |
Splenic involvement | |||||||
No | 44 | 97.6 | 97.6 | 94.8 | 94.8 | NA | 0.013 |
Yes | 25 | 87.5 | 77.7 | 77.7 | 66.6 | NA | |
Bone marrow involvement | |||||||
No | 62 | 93.3 | 89.7 | 87.5 | 87.5 | NA | 0.950 |
Yes | 7 | 100 | 100 | 100 | 80.0 | NA | |
Lung involvement | |||||||
No | 63 | 93.5 | 91.8 | 89.9 | 84.6 | NA | 0.371 |
Yes | 6 | 100 | 66.7 | NA | NA | NA | |
Bulky disease | |||||||
No | 56 | 94.4 | 90.4 | 88.1 | 80.1 | NA | 0.595 |
Yes | 13 | 92.3 | 92.3 | 92.3 | 92.3 | NA | |
Stage | |||||||
I–II | 33 | 100 | 96.2 | 96.2 | 96.2 | NA | 0.029 |
III–IV | 36 | 88.2 | 81.4 | 81.4 | 73.3 | NA | |
B symptoms | |||||||
No | 45 | 100 | 97.6 | 94.7 | 86.1 | NA | 0.059 |
Yes | 24 | 82.6 | 77.1 | 77.1 | 77.1 | NA | |
CMT | |||||||
No | 47 | 93.3 | 90.7 | 87.6 | 87.6 | NA | 0.909 |
Yes | 22 | 95.5 | 90.9 | 90.9 | 83.3 | NA | |
Histopathology subtypes | |||||||
MC | 29 | 100 | 100 | 100 | 100 | NA | 0.005 |
NS | 36 | 88.2 | 81.7 | 78.0 | 66.8 | NA | |
Radiotherapy dose | |||||||
15 | 15 | 93.3 | 86.7 | 86.7 | 74.3 | NA | 0.196 |
20 | 7 | 100 | 100 | 100 | 100 | NA | |
Interim PET-CT | |||||||
No | 60 | 93.2 | 91.4 | 91.4 | 84.8 | NA | 0.351 |
Yes | 9 | 100 | 87.5 | 74.1 | 74.1 | NA | |
Interim negative & CMT | |||||||
No | 43 | 100 | 90 | 90 | 90 | 80.7–99.2 | 0.719 |
Yes | 17 | 94 | 94 | 88.2 | 88.2 | 72.9–100 | |