Fig. 4
From: CircMCTP2 enhances the progression of bladder cancer by regulating the miR-99a-5p/FZD8 axis
FZD8 was the novel downstream molecule of miR-99a-5p. A The complementary fragments between miR-99a-5p and the 3’-UTR of FZD8 were predicted. B Assay was conducted to evaluate the interaction between FZD8 and miR-99a-5p. C Upregulation of miR-99a-5p was detected after the treatment with miR-99q-5p mimics. D-F Both the mRNA and protein levels of FZD8 were examined in T24 and RT-4 cells following the treatment with miR-NC or miR-99a-5p mimics. G The expression levels of FZD8 were notably elevated in bladder cancer specimens. H The expression of miR-99a-5p and FZD8 were negatively correlated in bladder cancer samples. *P < 0.05