Fig. 5
From: CircMCTP2 enhances the progression of bladder cancer by regulating the miR-99a-5p/FZD8 axis
MiR-99a-5p suppressed the growth of bladder cancer cells through regulating the FZD8/Wnt-b-catenin axis. A-C Transfection with oe-FZD8 increased the expression of FZD8. D and E The influences of miR-99a-5p mimics and co-transfection with miR-99a-5p mimics and oe-FZD8 on the proliferation of T24 and RT-4 cells were examined. F and G The impacts of miR-99a-5p mimics and co-transfection with miR-99a-5p mimics and oe-FZD8 on migratory/invasive activities of bladder cancer cells were determined by Transwell method. H and I The apoptosis of T24 and RT-4 cells following the transfection with miR-99a-5p mimics or co-transfection with miR-99a-5p mimics and oe-FZD8 were elucidated. *P < 0.05