Table 3 Association of the NME1 rs34214448 variant with clinicopathological characteristics

Age (years)

  < 50

8/17

16/19

4/8

1.06 (0.24–4.59); 1.000

1.78 (0.61–5.22); 0.422

1.57 (0.56–4.36); 0.534

  > 50

43/82

128/85

33/21

2.99 (1.54–5.79); 0.001

2.87 (1.81–4.54); 0.001

2.89 (1.85–4.51); 0.001

Sex

 Male

33/50

79/46

22/13

2.56 (1.13–5.78); 0.036

2.60 (1.47–4.60); 0.001

2.59 (1.50–4.47); 0.001

 Female

18/49

65/58

15/16

2.55 (1.05–6.20); 0.061

3.05 (1.59–5.81); 0.001

2.94 (1.57–5.50); 0.001

TNM stage

 I + II

15/99

44/104

10/29

2.27 (0.92–5.60); 0.116

2.79 (1.46–5.33); 0.002

2.67 (1.42–5.02); 0.002

 III + IV

36/99

100/104

27/29

2.56 (1.33–4.89); 0.006

2.64 (1.65–4.23); 0.001

2.62 (1.67–4.12); 0.001

Localization

 Colon

28/99

70/104

10/29

1.21 (0.53–2.80); 0.803

2.37 (1.41–3.99); 0.001

2.12 (1.28–3.51); 0.004

 Rectum

23/99

74/104

27/29

4.00 (2.00–8.01); 0.001

3.06 (1.77–5.27); 0.001

3.26 (1.93–5.51); 0.001