Table 4 Association of the NME1 rs2302254 variant with clinicopathological characteristics

Age (years)

  < 50

3/15

17/23

8/6

6.66 (1.30–34.02); 0.043

3.69 (0.92–14.82); 0.106

4.31 (1.11–16.62); 0.050

  > 50

51/50

107/102

46/36

1.25 (0.69–2.24); 0.544

1.02 (0.63–1.65); 1.000

1.08 (0.69–1.70); 0.806

Sex

 Male

36/36

63/55

35/18

1.94 (0.93–4.04); 0.108

1.14 (0.63–2.05); 0.761

1.34 (0.77–2.33); 0.365

 Female

18/29

61/70

98/24

6.57 (3.14–13.76); 0.001

1.40 (0.71–2.77); 0.419

2.72 (1.43–5.17); 0.002

TNM stage

 I + II

14/65

36/125

19/42

2.10 (0.95–4.63); 0.097

1.33 (0.67–2.65); 0.507

1.52 (0.79–2.93); 0.260

 III + IV

40/65

88/125

35/42

1.35 (0.74–2.46); 0.398

1.14 (0.70–1.84); 0.668

1.19 (0.75–1.89); 0.512

Localization

 Colon

24/65

51/125

32/42

2.06 (1.07–3.97); 0.044

1.10 (0.62–1.95); 0.842

1.34 (0.78–2.30); 0.340

 Rectum

29/65

73/125

22/42

1.17 (0.59–2.30); 0.770

1.30 (0.77–2.21); 0.380

1.27 (0.76–2.11); 0.413