Skip to main content

Table 6 Association of the DCC rs714 variant with clinicopathological characteristics

From: NME1 and DCC variants are associated with susceptibility and tumor characteristics in Mexican patients with colorectal cancer

DCC rs714 A < G

 

CRC/Control

OR (95% CI); P value

Variable

AA

AG

GG

GG versus AA

AG versus AA

AG + GG versus AA

Age (years)

  < 50

3/12

21/21

4/11

1.45 (0.26–8.00); 1.000

4.00 (0.98–16.25); 0.086

3.12 (0.79–12.28); 0.164

  > 50

42/45

109/87

53/56

1.01 (0.57–1.78); 1.000

1.34 (0.80–2.22); 0.311

1.21 (0.75–1.95); 0.499

Sex

 Male

32/28

73/48

29/33

0.76 (0.37–1.56); 0.586

1.33 (0.71–2.48); 0.460

1.10 (0.61–1.97); 0.86

 Female

13/29

57/60

28/34

1.83 (0.80–4.18); 0.211

2.11 (1.00–4.47); 0.070

2.01 (0.98–4.13); 0.077

TNM stage

 I + II

16/57

32/108

21/67

1.11 (0.53–2.34); 0.917

1.05 (0.53–2.08); 1.000

1.07 (0.57–2.03); 0.940

 III + IV

29/57

73/108

40/67

1.17 (0.64–2.12); 0.706

1.32 (0.77–2.27); 0.366

1.26 (0.76–2.10); 0.424

Localization

 Colon

19/57

64/108

25/67

1.11 (0.55–2.23); 0.886

1.77 (0.97–3.25); 0.08

1.52 (0.85–2.72); 0.194

 Rectum

26/57

66/108

32/67

1.04 (0.55–1.95); 1.000

1.32 (0.76–2.33); 0.371

1.22 (0.72–2.07); 0.526

  1. P-value were adjusted by the Bonferroni test (0.0125). Bold text highlights statistically significant findings