NME1 and DCC variants are associated with susceptibility and tumor characteristics in Mexican patients with colorectal cancer

Journal of the Egyptian National Cancer Institute

Table 7 Logistic Regression Analysis for the NME1 and DCC variants analyzed with confounding variables

Independent Variable	Regression Coefficient	Standard Error	Wald Test	Degrees of Freedom	P value	OR (95% IC)
Age > 50 vs. < 50	0.442	0.280	2.482	1	0.115	1.55 (0.89 -2.69)
Sex Male vs. Female	0.422	0.201	4.428	1	0.035	1.52 (1.02 -2.26)
Smoking status Yes vs. No	0.742	0.243	9.358	1	0.002	2.10 (1.30 -3.37)
Drinking status Yes vs. No	0.725	0.264	7.522	1	0.006	2.06 (1.23 -3.46)
NM23 rs34214448 GT + TT	0.858	0.217	15.688	1	0.001	2.35 (1.54 -3.60)
DCC rs2229080 GC + CC	0.637	0.228	7.806	1	0.005	1.89 (1.21–2.95)
Constant	-1.862	0.307	36.873	1	0.001
Model	X² = 63.475 d.f. = 6 P = 0.001

Bonferroni test was used to adjust the P value (0.0125); Bold values indicate statistically significant findings