Investigating the level of vitamin D receptor gene expression in two tumoral and healthy breast tissues in breast cancer patients and its association with prognostic factors

Journal of the Egyptian National Cancer Institute

Table 2 Examination of vitamin D receptor gene expression levels in two tumoral and healthy tissues according to tumor grade, HER2, ER, PR, LVI, LN, and disease stage

Tissue	Variable		Vitamin D receptor gene expression level
Tissue	Variable		Average	Standard deviation	Mean	Quartile range	P
Tumoral	Tumor grade	1	1.23	3.45	0.01	0.02	0.9
		2	0.04	0.08	0.01	0.04
		3	0.1	0.20	0.01	0.08
Healthy		1	2.35	0.7	2.08	1.21	0.58
		2	2.04	0.79	2.09	0.98
		3	2	1.37	1.98	1.35
Tumoral	HER2	Positive	0.04	0.08	0.01	0.03	0.73
Tumoral		Negative	0.32	1.58	0.01	0.05	0.73
Healthy		Positive	2.32	1.02	2.25	0.92	0.19
Healthy		Negative	2	1.01	2.02	0.9	0.19
Tumoral	ER	Positive	0.36	1.72	0.01	0.04	0.66
Tumoral		Negative	0.06	0.11	0.01	0.05	0.66
Healthy		Positive	2.03	0.87	2.05	0.63	0.91
Healthy		Negative	2.15	1.25	2.04	1.29	0.91
Tumoral	PR	Positive	0.43	1.87	0.01	0.05	0.77
Tumoral		Negative	0.05	0.1	0.01	0.03	0.77
Healthy		Positive	2.02	0.92	2.04	0.65	0.65
Healthy		Negative	2.14	1.13	2.05	1.2	0.65
Tumoral	LVI	Positive	0.26	1.41	0.01	0.04	0.52
Tumoral		Negative	0.1	0.19	0.14	0.004	0.52
Healthy		Positive	2.07	1.03	2.04	0.9	0.79
Healthy		Negative	2.14	0.31	2.14	1.91	0.79
Tumoral	LN	N0	0.04	0.07	0.01	0.03	0.81
		N1	0.94	2.93	0.01	0.05
		N2	0.14	0.27	0.01	0.22
		N3	0.03		0.03	0
Healthy		N0	1.96	0.98	2.04	0.9	0.36
		N1	2.56	1.11	2.05	1.27
		N2	1.76	0.93	1.98	1.2
		N3	2.78		2.78	0
Tumoral	Disease stage	1A	0.006	0.004	0.003	0.003	0.66
		2A	0.04	0.08	0.01	0.01
		2B	1.47	3.66	0.055	0.42
		3A	0.1	0.23	0.01	0.04
		3B	0.003		0.003	0
		3C	0.03		0.03	0
Healthy		1A	2.63	0.86	2.49	1.84	0.35
		2A	1.95	1.01	2.05	0.91
		2B	2.52	1.37	2.11	1.35
		3A	2.09	0.6	2.04	0.67
		3C	2.78		2.78	0