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Table 8 Outcome of postoperative chemoradiotherapy in HNSCC patients by previous reports

From: Patterns of recurrence after low-dose postoperative radiotherapy for head and neck squamous cell carcinoma

Author

Year

No. of patients

Risk

ECE (%)

Treatment

RT (Gy)

LRC or LRR (%)

OS (%)

Close/positive margin (%)

(year)

(year)

Bernier et al.

2004

167

31

61

CRT

66

LRR 18 (5)

53 (5)

167

26

53

RT

66

LRR 31 (5)

40 (5)

Cooper et al.

2004

206

17

< 83

RT

60‑66

82 (2)

56 (3)

210

19

< 81

CRT

60‑66

72 (2)

47 (3)

Yao et al.

2005

49

NR

NR

CRT

54‑66

82 (2)

NR

Chan et al.

2013

180

17

34

CRT

54‑66

78 (2)

65 (2)

Ooishi et al.

2016

122

30

77

RT/CRT

66

52 (3)

59 (3)

Makita et al.

2017

89

37

81

RT/CRT

60 (median)

83 (2)

72 (2)

Present

2021

90

9

19

RT/CRT

50.4 (median)

82.7 (3)

67.5 (3)

  1. HNSCC head and neck squamous cell carcinoma, ECE extracapsular extension, RT radiation therapy, CRT chemoradiotherapy, LRC locoregional failure, LRR locoregional recurrence, OS overall survival, NR not reported