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Fig. 4 | Journal of the Egyptian National Cancer Institute

Fig. 4

From: Significance of OCT3/4 and SOX2 antigens expression by leukemic blast cells in adult acute leukemia

Fig. 4

ROC curve (A) to identify the optimal SOX2 and OCT3/4 expression cutoff value that predicts death in ALL (best cut-off for SOX2 > 16.3% with AUC 0.763, P = 0.006, sensitivity 70.6% and specificity 66.7%) and (best cut-off for OCT3/4 > 1.55% with AUC of 0.758, P = 0.007, sensitivity 70.6% and specificity 71.4%). B To identify the optimal SOX2 and OCT3/4 expression cutoff value that predicts death in AML (best cut-off for SOX2 > 21.7% with AUC 0.854, P = < 0.001, sensitivity 88.0% and specificity 82.4%) and (best cut-off for OCT3/4 > 1.65% with AUC of 0.692, P = 0.037, sensitivity 68.0% and specificity 70.6%)

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