Skip to main content

Table 7 Cox regression analysis to predict the hazardous factor that could predict OS in ALL patients

From: Significance of OCT3/4 and SOX2 antigens expression by leukemic blast cells in adult acute leukemia

Parameter

Univariable

Multivariable

P

HR

95% CI

P value

HR

95% CI

Age (years)

0.022

1.035

1.005–1.066

0.146

1.031

0.989–1.074

Gender

0.439

1.486

0.545–4.054

   

WBCs × 109/L

0.227

1.133

0.925–1.387

   

Hemoglobin g/dl

0.674

0.998

0.990–1.007

   

Platelets count × 109/L

0.206

0.985

0.961–1.009

   

BM blast cells %

0.118

1.006

0.989–1.011

   

Risk stratification (unfavorable vs favorable)

0.011

7.926

2.234–28.125

0.120

3.703

0.710–19.299

Response (non-CR vs CR)

< 0.001

15.442

4.792–49.773

0.021

5.432

1.286–22.955

Relapse (relapsed vs non-relapsed)

0.522

1.585

0.387–6.490

   

SOX2 expression (%)

0.001

1.041

1.017–1.066

0.029

1.029

1.003–1.056

OCT3/4 expression (%)

0.004

1.070

1.022–1.121

0.018

1.084

1.014–1.158

  1. HR Hazard ratio, CI Confidence interval, (r) Reference group