Table 9 Cox regression analysis to predict the hazardous factor that could predict OS in AML patients

Age (years)

0.785

1.003

0.984–1.022

Gender

0.784

1.117

0.506–2.464

WBCs × 10⁹/L

0.827

1.001

0.955–1.006

Hemoglobin g/dl

0.657

0.952

0.767–1.182

Platelets count × 10⁹/L

0.367

0.996

0.989–1.004

Bone marrow blast %

0.218

1.003

0.989–1.008

Risk stratification

 Favorable

R

1

–

R

1

–

 Intermediate

0.027

4.535

1.190–17.287

0.118

3.200

0.744–13.760

 Poor

< 0.001

24.463

6.283–95.244

0.187

4.425

0.982–40.220

Response (non-CR vs CR)

< 0.001

10.294

4.107–25.802

0.052

6.078

0.982–37.634

Relapse (relapsed vs non-relapsed)

0.471

1.494

0.502–4.450

SOX2 expression (%)

< 0.001

1.034

1.019–1.050

0.001

1.033

1.014–1.054

OCT3/4 expression (%)

0.001

1.179

1.027–1.353

0.045

1.163

1.021–1.339