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  1. Angiogenesis is the formation of new vascular networks from preexisting ones through the migration and proliferation of differentiated endothelial cells. Available evidence suggests that while antiangiogenic t...

    Authors: Ayodipupo S. Oguntade, Faez Al-Amodi, Abdullah Alrumayh, Muath Alobaida and Mwango Bwalya
    Citation: Journal of the Egyptian National Cancer Institute 2021 33:15
  2. Aberrant T cell antigen expression has been well documented in diffuse large B cell lymphomas. However, co-expression of multiple T cell antigens including CD3, which has been considered a specific marker for ...

    Authors: Anurag Mehta, Prerna Chadha, Poojan Agarwal and Sunil Pasricha
    Citation: Journal of the Egyptian National Cancer Institute 2021 33:14
  3. The burden of cancer in Sri Lanka is on the rise. The overall incidence of cancer in Sri Lanka has doubled over the past 25 years with a parallel rise in cancer-related mortality. Cancer has become the second ...

    Authors: Umesh Jayarajah and Anuruddha M. Abeygunasekera
    Citation: Journal of the Egyptian National Cancer Institute 2021 33:13
  4. Acute oral mucositis has been infrequently studied in the patients with head and neck squamous cell carcinoma (HNSCC) receiving once-weekly cisplatin-based chemoradiotherapy (CRT). Hence, this analysis was con...

    Authors: Vanita Noronha, Vijay M. Patil, Gunjesh Kumar Singh, Amit Joshi, Nandini Menon, Sarbani Ghosh Lashkar, Vijayalakshmi Mathrudev, Kavita Nawale Satam and Kumar Prabhash
    Citation: Journal of the Egyptian National Cancer Institute 2021 33:12
  5. Breast cancer (BC) is the 2nd most prevalent malignancy worldwide and is the most prevalent cancer among Egyptian women. The number of newly described cancer-associated genes has grown exponentially since the eme...

    Authors: Neemat Kassem, Hebatallah Kassem, Loay Kassem and Mohamed Hassan
    Citation: Journal of the Egyptian National Cancer Institute 2021 33:10
  6. Intensive acute lymphoblastic leukemia (ALL) regimens in children improve the 5-year event-free survival (EFS) to reach ~ 90%. Adolescents and young adults (AYA) have EFS (30% to 45%). Young AYA ALL patients t...

    Authors: Hossam Eldin A. Elashtokhy, Heba E. Elgohary, Basant B. Eldeep, Sally M. Gaber and Tamer A. Elbedewy
    Citation: Journal of the Egyptian National Cancer Institute 2021 33:9
  7. Acral vascular syndrome clinically presents as digital ischemia with Raynaud’s phenomenon and erythromelalgia but can be rarely seen in the malignant condition. Patients may present pain, permanent digital bla...

    Authors: Kamal Bandhu Klanidhi, S. Ashwin Monian and Avinash Chakrawarty
    Citation: Journal of the Egyptian National Cancer Institute 2021 33:8
  8. In 2018, leukaemia accounted for 2.6% of all new cancers, it being the 13th most common cause of cancer and the 10th most common cause of cancer death. Glucocorticoids are commonly used in lymphoid leukaemia t...

    Authors: Mariah Farrugia, Catriona Cutajar, Jean Calleja Agius and Pierre Schembri Wismayer
    Citation: Journal of the Egyptian National Cancer Institute 2021 33:7
  9. Medulloblastoma (MB) is a heterogeneous disease, displaying distinct genetic profiles with specific molecular subgroups. This study aimed to validate MB molecular subgrouping using surrogate immunohistochemist...

    Authors: Asmaa Mustafa Eid and Nehal Abd El-Ghaffar Heabah
    Citation: Journal of the Egyptian National Cancer Institute 2021 33:6
  10. Management of the node-positive axilla after neoadjuvant chemotherapy is controversial. The aim of this study is to predict the group of patients who may require a less invasive approach for axillary managemen...

    Authors: Mina M. G. Youssef, Ahmed A. Metwally and Tamer M. Manie
    Citation: Journal of the Egyptian National Cancer Institute 2021 33:5
  11. Osteosarcoma (OS) is one of the key cancers affecting the bone tissues, primarily occurred in children and adolescence. Recently, chemotherapy followed by surgery and then post-operative adjuvant chemotherapy ...

    Authors: Sujit Arun Desai, Arehalli Manjappa and Preeti Khulbe
    Citation: Journal of the Egyptian National Cancer Institute 2021 33:4
  12. Vaginal metastasis should be kept in mind when evaluating the staging tests of all cancers, especially endometrial cancer.

    Authors: Mustafa Korkmaz, Melek Karakurt Eryılmaz, Ülkü Kerimoğlu, Mustafa Karaağaç, Aykut Demirkıran, Emine Türen Demir and Mehmet Artaç
    Citation: Journal of the Egyptian National Cancer Institute 2021 33:3
  13. The number of people with implanted hip prosthesis has grown worldwide. For radiotherapy planning of patients with hip implants, few main challenges are encountered. The aim of the present study was to evaluat...

    Authors: Manindra Bhushan, Deepak Tripathi, Girigesh Yadav, Lalit Kumar, Rahul Lal Chowdhary, Anjali K. Pahuja, Tamilarasu Suresh, Sushil Kumar Shukla and Swarupa Mitra
    Citation: Journal of the Egyptian National Cancer Institute 2021 33:2
  14. Renal angiomyoadenomatous tumor (RAT) is a recently described rare renal neoplasm with variations in the presentation, gross, and microscopic findings, and having a benign course and good prognosis. It is char...

    Authors: Ankur Majumder, Ravi Hari Phulware, Arvind Ahuja, Anurag Singla and Pawan Kumar
    Citation: Journal of the Egyptian National Cancer Institute 2021 33:1
  15. Urinary schistosomiasis and its severe complications, mainly bladder cancer, are scarce in non-endemic areas. The deficiency in knowledge and clinical experience of schistosomiasis may lead to inadequate manag...

    Authors: Mohamed S. Zaghloul, Tarek M. Zaghloul, Mai K. Bishr and Brian C. Baumann
    Citation: Journal of the Egyptian National Cancer Institute 2020 32:44
  16. Multiple myeloma (MM) is a human B cell neoplasia characterized by the clonal proliferation of malignant plasma cells in the bone marrow. Worldwide, hepatitis C virus (HCV) infection is a public health problem...

    Authors: Neemat M. Kassem, Hebatallah A. Kassem, Magdy Ibrahim, Hussam Zawam and Emad Hamada
    Citation: Journal of the Egyptian National Cancer Institute 2020 32:43
  17. Podophyllotoxin (PPT) is a naturally occurring compound obtained from the roots of Podophyllum species, indicated for a variety of malignant tumors such as breast, lung, and liver tumors. This toxic polyphenol...

    Authors: Popat S. Kumbhar, Asmita M. Sakate, Onkar B. Patil, Arehalli S. Manjappa and John I. Disouza
    Citation: Journal of the Egyptian National Cancer Institute 2020 32:42
  18. Endometrial carcinoma is one of the most common female cancers in developed countries. Disease stage is associated with the risk of disease relapse after radical treatment. Typically, the risk of disease relap...

    Authors: Leonardo Muratori, Paola Sperone, Gabriella Gorzegno, Anna La Salvia and Giorgio Vittorio Scagliotti
    Citation: Journal of the Egyptian National Cancer Institute 2020 32:41
  19. To identify and report flaws of Internet-published articles in the Journal of the Egyptian National Cancer Institute (JENCI), Cairo University, through a retrospective documentary study on articles published duri...

    Authors: Sarah S. Nasr, Ghada M. Sherif, Amal S. Ibrahim and Rasha M. Allam
    Citation: Journal of the Egyptian National Cancer Institute 2020 32:39
  20. Primary malignant melanoma of the female urethra is an exceedingly rare tumor. It represents 0.2% of all malignant melanomas. Divergent differentiation towards non-melanocytic lineages has not been reported in...

    Authors: Tripti Nakra, Rohit Dadhwal, Rishi Nayyar, Sameer Rastogi, Aanchal Kakkar, Mehar Chand Sharma and Rajni Yadav
    Citation: Journal of the Egyptian National Cancer Institute 2020 32:40
  21. Glutathione can reduce the oxidative stress by converting the unstable to stable molecules and its status in hepatocellular carcinoma (HCC) is correlated with tumor growth and metastasis.

    Authors: Shaimaa Gamal Hassan Elofey, Nevine F. Shafik, Noha Hassan Radwan, Osman Mohammed Mansour, Rasha Mahmoud Allam, Samia Shouman and Iman Attia AbdelGawad
    Citation: Journal of the Egyptian National Cancer Institute 2020 32:38
  22. The study investigated the expression and the clinicopathological significance of p53, p27, Ki-67, E-cadherin, and HER2 in upper urinary tract urothelial carcinomas (UTUC) from Tunisian patients. We performed ...

    Authors: Nabiha Missaoui, Ahlem Bdioui, Atika Baccouche, Oussema Belkacem, Wissem Hmida, Moncef Mokni and Sihem Hmissa
    Citation: Journal of the Egyptian National Cancer Institute 2020 32:36
  23. The challenging target in the workup of thyroid nodule(s) is to exclude or diagnose thyroid cancer efficiently prior to surgical intervention. The present work studied a panel of eight serum biomarkers to diff...

    Authors: Ragaa Abdelkader Ramadan, Wafaa Ragab, Ramy Samir Assaad, Ahmed Elsayed Shaaban and Amira Ibrahim Fayad
    Citation: Journal of the Egyptian National Cancer Institute 2020 32:35
  24. Telomere stability is one of the hallmarks of cancer that promotes cellular longevity, the accumulation of genetic alterations, and tumorigenesis. The loss of death domain-associated protein (DAXX) and α-thala...

    Authors: Marwa T. Hussien, Shimaa Shaban, Doaa F. Temerik, Shaaban R. Helal, Eman Mosad, Sahar Elgammal, Abeer Mostafa, Eman Hassan and Abeer Ibrahim
    Citation: Journal of the Egyptian National Cancer Institute 2020 32:34
  25. Wilms’ tumor (WT) represents about 6% of all childhood cancers. The overall survival markedly improved to exceed 90% in developed countries, yet some studies from developing counties still have poorer outcomes...

    Authors: Hosam Y. Asfour, Sahar A. Khalil, Al-Shimaa Zakaria, El-Sayed Ashraf and Wael Zekri
    Citation: Journal of the Egyptian National Cancer Institute 2020 32:32
  26. Absolute monocyte count (AMC) correlates with survival outcomes in various hematologic malignancies. However, its role in myeloid malignancies including AML needs to be highlighted. So, this prospective cohort...

    Authors: Ahmed Embaby, Ayman Fathy, Mohammad Al-Akkad, Ahmad Baraka, Taiseer Ibrahim, Nahla Zidan, Mohamed Refaat and Haitham Elsheikh
    Citation: Journal of the Egyptian National Cancer Institute 2020 32:33
  27. To evaluate the dosimetric impact of variable bladder filling on target and organ at risk (OARs) in cervical cancer patients undergoing chemoradiation. Forty consecutive patients with cervical cancer underwent...

    Authors: Soumya Dutta, Abhinav Dewan, Swarupa Mitra, Manoj Kumar Sharma, Sumeet Aggarwal, Soumitra Barik, M. Mahammood Suhail, Maninder Bhushan, Anurag Sharma, Inderjeet Kaur Wahi, Kiran Dobriyal and Jwala Mukhee
    Citation: Journal of the Egyptian National Cancer Institute 2020 32:31
  28. Colorectal carcinoma still represents a global health burden despite the advances in its management. The most common sites of distant metastasis from colorectal carcinoma are hepatic and pulmonary metastases w...

    Authors: Reham Alghandour, Gehad A. Saleh, Farida Ahmed Shokeir and Mohammad Zuhdy
    Citation: Journal of the Egyptian National Cancer Institute 2020 32:30
  29. The phyllodes tumors are rare neoplastic disease which exhibits a benign behavior in adolescents female. After resection of a large benign breast tumor, insufficient breast contour may result with nipple areol...

    Authors: Mahmoud A. Hifny, Mohamed Yousef A., Asmaa Gaber R., Mohamed Abdelshafy Mohamed and Mahmoud Abdelhameid
    Citation: Journal of the Egyptian National Cancer Institute 2020 32:27
  30. Postmastectomy lymphedema can be considered the main cause of upper extremity functional impairment in patients with breast cancer. Fatigue, pain, and limited range of motion are common symptoms. If left untre...

    Authors: Doaa Atef, Mohmed Maher Elkeblawy, Ashraf El-Sebaie and Walid Ahmed Ibrahim Abouelnaga
    Citation: Journal of the Egyptian National Cancer Institute 2020 32:29
  31. Allogeneic hematopoietic stem cell transplantation (Allo-HSCT) is a curative treatment for adult patients with acute lymphoblastic leukemia (ALL). Cyclophosphamide plus total body irradiation (TBI/Cy) or plus ...

    Authors: Mona Mahrous Abdelaty, Amr Gawaly, Gamal M. Fathy, Ibrahim Kabbash and Atef Taha
    Citation: Journal of the Egyptian National Cancer Institute 2020 32:28
  32. Inflammatory myofibroblastic tumor (IMT) is a mesenchymal tumor mainly found in lung or retroperitoneum and rarely affects head and neck region. Extensive English literature search reveals that less than fifty...

    Authors: Rituparna Biswas, Anirban Halder, Mimi Gangopadhyay and Dipanwita Biswas
    Citation: Journal of the Egyptian National Cancer Institute 2020 32:26
  33. Adrenal tumors can be detected incidentally in 4 to 8% of patients radiologically. Adenomas, pheochromocytomas, and adrenocortical carcinomas represent the most common tumors of the adrenal glands. Rare histop...

    Authors: M. A. Elbaset, Mohamad H. Zahran, Mohamed Badawy, M. Abd Elhameed and Yasser Osman
    Citation: Journal of the Egyptian National Cancer Institute 2020 32:25
  34. NME1 and KISS1 genes are two tumor metastasis suppressor genes, mapped to chromosomes 17q21.3 and 1q32 respectively. Here, we analyzed the association of EcoR1 (rs34214448—G/T) polymorphism in NME1 gene and 9 ...

    Authors: Sarah Antar, Naglaa Mokhtar, Mahmoud Adel Abd elghaffar and Amal K. Seleem
    Citation: Journal of the Egyptian National Cancer Institute 2020 32:24
  35. Central neurocytomas represent 0.25–0.5% of all intracranial tumors in adults. Leptomeningeal spread is uncommon, and the exact incidence of meningeal spread is unknown due to sparse literature. We present the...

    Authors: Shikha Goyal, Tejinder Kataria, Deepak Gupta, Aruj Dhyani, Ishani Mohapatra and Karanjit Singh Narang
    Citation: Journal of the Egyptian National Cancer Institute 2020 32:23
  36. Transformation of low-grade follicular lymphoma to high-grade diffuse large B cell lymphoma (DLBCL) is known. However, the opposite is not commonly reported. In this report, we present a case of follicular lym...

    Authors: M. C. Suresh Babu, Antony George Francis Thottian, D. Lokanatha, Linu Abraham Jacob, K. N. Lokesh, A. H. Rudresha, L. K. Rajeev, Saldanha Smitha, Syed Adil Hassan, Khandare Pravin Ashok, C. S. Premalatha and M. N. Suma
    Citation: Journal of the Egyptian National Cancer Institute 2020 32:22
  37. Wilms’ tumor (WT) affects one in 10,000 children and accounts for 5% of all childhood cancers. Although the overall relapse rate for children with WT has decreased to less than 15 %, the overall survival for p...

    Authors: Wael Zekri, Dalia M. Yacoub, Asmaa Ibrahim and Youssef Madney
    Citation: Journal of the Egyptian National Cancer Institute 2020 32:21
  38. The known efficacy of doxorubicin in metastatic breast cancer is countered by its dose-limiting myelosuppression and cardiotoxicity. Pegylated liposomal doxorubicin (PLD) was discovered to overcome these probl...

    Authors: Salah Mabrouk Khallaf, Jasmine Roshdy and Abeer Ibrahim
    Citation: Journal of the Egyptian National Cancer Institute 2020 32:20
  39. Wilms’ tumor (WT) is the most common renal malignant tumor of childhood. Metastatic WT has a worse prognosis than localized disease. This study aims to assess the clinical outcome and different prognostic fact...

    Authors: Moatasem Elayadi, Sarah Magdy, Ehab Khalil and Wael Zekri
    Citation: Journal of the Egyptian National Cancer Institute 2020 32:19
  40. Tumor-associated macrophages (TAM) are pivotal in remodeling of the tumor immune microenvironment and clinical outcome. Herein, we aim to evaluate the impact of immunohistochemical (IHC) expression of CD68 and...

    Authors: Mona Y. Y. Abd Allah, Maryan Waheeb Fahmi and Shaimaa EL-Ashwah
    Citation: Journal of the Egyptian National Cancer Institute 2020 32:18
  41. The focus of trastuzumab resistance biomarkers in recent decades has been on epigenetic and non-coding RNA-based mechanisms. In this study, the potential of miR-494 and its target genes as predictive biomarker...

    Authors: Adam Hermawan and Herwandhani Putri
    Citation: Journal of the Egyptian National Cancer Institute 2020 32:16
  42. Acute myeloid leukemia (AML) can modulate toll-like receptor-9 (TLR9) expression and activation. This study was conducted to elucidate the expression of TLR9 in AML patients and its relation to the prognosis o...

    Authors: Waiel M. A. Al-Kahiry, Enas A. M. Dammag, Hadeel S. T. Abdelsalam, Hayat K. Fadlallah and Mona S. Owais
    Citation: Journal of the Egyptian National Cancer Institute 2020 32:15
  43. The Oncotype DX is a quantitative assay of the expression of 16 tumor-related genes and 5 reference genes that predicts the potential of adjuvant chemotherapy benefit in estrogen receptor (ER)-positive early b...

    Authors: Salah Fayaz, Heba El-Sayed Eissa and Gerges Attia Demian
    Citation: Journal of the Egyptian National Cancer Institute 2020 32:13
  44. Squamous cell carcinoma of the oral cavity (OSCC) is the sixth most common malignancy. Surgery is mainstay treatment for oral cancers. Surgery in locally advanced OSCC presents many challenges primarily becaus...

    Authors: Diani Kartini, Akmal Taher, Sonar Soni Panigoro, Rianto Setiabudy, Sri Widia Jusman, Sofia Mubarika Haryana, Murdani Abdullah, Primariadewi Rustamadji, Denni Joko Purwanto, Noorwati Sutandyo, Indrati Suroyo, Budi Harapan Siregar, Haris Maruli and Saleha Sungkar
    Citation: Journal of the Egyptian National Cancer Institute 2020 32:12
  45. Hepatic complications are a well-known cause of both early and late mortality and morbidity in hematopoietic stem cell transplant (HSCT) recipients. Early diagnosis and management of hepatic complications is i...

    Authors: Haitham Abdelbary, Rasha Magdy, Mohammed Moussa and Inas Abdelmoaty
    Citation: Journal of the Egyptian National Cancer Institute 2020 32:11
  46. Treatment for malignant embryonal brain tumors in young children usually employs cycles of standardly dosed cisplatinum followed by high-dose carboplatinum-containing conditioning with single or tandem autolog...

    Authors: Yasser Elborai, Mohammad Almutereen, Ossama M. Maher, Hanafy Hafez, Michelle A. Lee and Leslie Lehmann
    Citation: Journal of the Egyptian National Cancer Institute 2020 32:9

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