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Journal of the Egyptian National Cancer Institute
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  1. Glioblastoma (GBM) is a fatal, fast-growing, and aggressive brain tumor arising from glial cells or their progenitors. It is a primary malignancy with a poor prognosis. The current study aims at evaluating the...

    Authors: H. Shafeeq Ahmed, Trupti Devaraj, Maanini Singhvi, T. Arul Dasan and Priya Ranganath
    Citation: Journal of the Egyptian National Cancer Institute 2024 36:13
    Content type: Research Published on:

  2. Breast cancer is one of the most common cancers known among women. This study aimed to investigate the level of vitamin D receptor gene expression in two tumoral and healthy breast tissues in breast cancer pat...

    Authors: Maryam Bahador, Marjan Saeedi Nejad, Shahriar Dabiri, Mohammad Hasan Larizadeh and Maryam Fekri Soofiabadi
    Citation: Journal of the Egyptian National Cancer Institute 2024 36:12
    Content type: Research Published on:

  3. The moderate deep inspiratory breath hold (mDIBH) is a modality famed for cardiac sparing. Prospective studies based on this are few from the eastern part of the world and India. We intend to compare the dosim...

    Authors: Anupam Muraleedharan, Sandip Kumar Barik, Deepak Kumar Das, Saroj Kumar Das Majumdar, Bikash Ranjan Mahapatra, Bijay Kumar Barik, Mathan Kumar Ramasubbu, Nehla Haroon K. M., Poornima Devi U., Sk Soel Ahmed, Priyanka Mukherjee, Ashutosh Pattanaik, Avinash Badajena, Minakshi Mishra, Satyabrata Kanungo, Sovan Sarang Dhar…
    Citation: Journal of the Egyptian National Cancer Institute 2024 36:11
    Content type: Research Published on:

  4. Colorectal cancer (CRC) ranks third in cancer incidence globally and is the second leading cause of cancer-related mortality. The nucleoside diphosphate kinase 1 (NME1) and netrin 1 receptor (DCC) genes have been...

    Authors: Rosa María Márquez-González, Anilú Margarita Saucedo-Sariñana, César de Jesús Tovar-Jacome, Patricio Barros-Núñez, Martha Patricia Gallegos-Arreola, Mario Humberto Orozco-Gutiérrez, Ignacio Mariscal-Ramírez, Tomas Daniel Pineda-Razo, Aldo Antonio Alcaraz-Wong, María Eugenia Marín-Contreras and Mónica Alejandra Rosales-Reynoso
    Citation: Journal of the Egyptian National Cancer Institute 2024 36:10
    Content type: Research Published on:

  5. Tumor-infiltrating lymphocytes (TILs) and the derived immunoscore (IS) have gained considerable attention over the last decade as prognostic markers in many solid cancers. However, in bladder cancer (BC), thei...

    Authors: Sarra Ben Rejeb, Sirine Elfekih, Nadia Kouki, Rami Boulma and Hassen Khouni
    Citation: Journal of the Egyptian National Cancer Institute 2024 36:9
    Content type: Research Published on:

  8. More and more genetic and metabolic abnormalities are now known to cause cancer, which is typically deadly. Any bodily part may become infected by cancerous cells, which can be fatal. Skin cancer is one of the...

    Authors: Devika Moturi, Ravi Kishan Surapaneni and Venkata Sai Geethika Avanigadda
    Citation: Journal of the Egyptian National Cancer Institute 2024 36:6
    Content type: Research Published on:

  10. Esophageal cancer has a poor survival outcome with 5-year OS at 16.7% despite treatment. Some inflammation-based prognostic indicators like the neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte r...

    Authors: Adrija Ghosh, Abhilash Dagar, Ram Pukar Bharat, Jaswin Raj, Dyuti Shah, Jyoti Sharma, Akash Kumar, Pritee A. Patil, Aman Sharma, Dayanand Sharma and Supriya Mallick
    Citation: Journal of the Egyptian National Cancer Institute 2024 36:4
    Content type: Research Published on:

  11. Targeted therapies against programmed death ligand-1 (PD-L1) in non-small cell lung cancer (NSCLC) have revolutionized the management in recent years. There is paucity of data on the significance of PD-L1 expr...

    Authors: Sindhu Kilaru, Soumya Surath Panda, Lalatendu Moharana, Debahuti Mohapatra, Satya Sundar G. Mohapatra, Adyakinkar Panda, Spoorthy Kolluri, Suma Devaraj and Ghanashyam Biswas
    Citation: Journal of the Egyptian National Cancer Institute 2024 36:3
    Content type: Research Published on:

  12. Metastatic tumors account for 80% of all lung tumors in children. Wilms tumour and osteosarcoma are the most tumors of childhood that produce lung metastases. The aim of the current study is to assess the prog...

    Authors: Asmaa Hamoda, Inas Elattar, Heba Mahmoud, Mohamed Abdelrahman and Emad Ebied
    Citation: Journal of the Egyptian National Cancer Institute 2024 36:2
    Content type: Research Published on:

  13. Breast cancer (BC) and its treatment affect women's tissue architecture and physiology, which leads to impaired muscle strength and joint dysfunction, affecting quality of life (QOL). Most evidence has focused...

    Authors: Alaa M. Ramadan, Abeer M. ElDeeb, Ahmed A. Ramadan and Dina M. Aleshmawy
    Citation: Journal of the Egyptian National Cancer Institute 2024 36:1
    Content type: Research Published on:

  14. Clinical utility of Ki-67 immunohistochemistry (IHC) in breast cancer (BC) is mainly limited to decide for the use of chemotherapy and estimate prognosis in patients with either Ki-67 index < 5% or > 30%; howe...

    Authors: Radhika Arora, Feroz Alam, Atia Zaka-ur-Rab, Veena Maheshwari, Kiran Alam and Mahboob Hasan
    Citation: Journal of the Egyptian National Cancer Institute 2023 35:43
    Content type: Research Published on:

  15. Limited data are available on metabolic syndrome and its relation to breast cancer risk in Egypt. We aimed to study metabolic syndrome and its individual components as risk of breast cancer.

    Authors: Amira M. Mohammed, Hosney B. Hamed, Maisa K. Noaman and Nelly Alieldin
    Citation: Journal of the Egyptian National Cancer Institute 2023 35:42
    Content type: Research Published on:

  16. Neuroblastoma, one of the most prevalent childhood cancers, is often treated with surgery, radiation, and chemotherapy. However, prognosis and survival are still dismal for children with neuroblastoma at high ...

    Authors: Qiang Wang, Wei Fan, ZengHui Hao, Bingxue Liang, Meili Fan, Zijian Zhao and Zhaozhu Li
    Citation: Journal of the Egyptian National Cancer Institute 2023 35:41
    Content type: Research Published on:

  17. Trousseau syndrome is a paraneoplastic syndrome associated with a risk of poor prognosis. We reviewed the survival time and prognosis of patients with Trousseau syndrome. We identified 40 cases from 28 reports...

    Authors: Munehiro Wakabayashi, Yoshinori Kikuchi, Kazuhisa Yamaguchi and Takahisa Matsuda
    Citation: Journal of the Egyptian National Cancer Institute 2023 35:40
    Content type: Systematic Review Published on:

  18. Early detection of colon cancer leads to better survival outcomes. This can be achieved through colorectal cancer (CRC) screening. People with a family history of cancer (FHC) have increased risk of developing...

    Authors: Maxwell Akonde, Eric Mishio Bawa, Ottovon Bismark Dakurah and Rajat Das Gupta
    Citation: Journal of the Egyptian National Cancer Institute 2023 35:38
    Content type: Research Published on:

  19. The second most deadly gynecological cancer worldwide, cervical cancer is steadily on the rise in sub-Saharan Africa, while vaccination programs are struggling to get off the ground. This systematic review’s a...

    Authors: Rogomenoma Alice Ouedraogo, Ali Kande, Wendyam Marie Christelle Nadembega, Djeneba Ouermi, Théodora Mahoukèdè Zohoncon, Florencia Wendkuuni Djigma, Charlemagne Marie Ragnag-Newende Ouedraogo, Olga Mélanie Lompo and Jacques Simpore
    Citation: Journal of the Egyptian National Cancer Institute 2023 35:39
    Content type: Review Published on:

  20. Gestational Trophoblastic Neoplasia (GTN) is a disease of the reproductive age group with an incidence rate of <1% among all tumors involving the female reproductive tract. It occurs because of aberrant fertil...

    Authors: Mehwish Shahzadi, Saqib Raza Khan, Muhammad Tariq, Sehrish Sarwar Baloch, Aisha Shahid, Munira Moosajee and Zarka Samon
    Citation: Journal of the Egyptian National Cancer Institute 2023 35:37
    Content type: Review Published on:

  21. The global spread of coronaviruses had a great impact on the economic and social situation of most countries. As the backbone of any society, the health sector made a significant contribution through applying ...

    Authors: Sarah S. Nasr, Ghada M. Sherif, Maha Abdel Wahab and Hatem Aboelkasem
    Citation: Journal of the Egyptian National Cancer Institute 2023 35:36
    Content type: Research Published on:

  23. Ameloblastic fibro-dentinoma is considered a rare, benign, mixed odontogenic tumor that occurs mainly in the posterior mandible in the 1st–2nd decade of life. Although the clinical behavior of Ameloblastic fib...

    Authors: Nihal Mohamed Ahmed Darwish, Hatem Wael Abdel-Fattah Amer and Nesma Nabil Mohamed Mahrous
    Citation: Journal of the Egyptian National Cancer Institute 2023 35:34
    Content type: Case Reports Published on:

  24. Chronic hepatitis B virus (HBV) infection is a serious global health concern, with an increased incidence and risk of developing cirrhosis and hepatocellular carcinoma (HCC). Patients chronically infected with...

    Authors: Ghada M. Al-Toukhy, Reda A. Suef, Sarah Hassan, Mohamed M. S. Farag, Tarek A. El-Tayeb and Mohamed T. M. Mansour
    Citation: Journal of the Egyptian National Cancer Institute 2023 35:33
    Content type: Research Published on:

  25. Gastric cancer (GC) is the one of the most commonly solid cancer worldwide. Although under the aggressive treatment, the poor clinical outcomes of patients with GCs have not been improved. Current studies emph...

    Authors: Mengxiao Lu, Yingjie Wu, Yixin Zhang, Yu Yu, ShengJie Wang and Xiaobao Su
    Citation: Journal of the Egyptian National Cancer Institute 2023 35:32
    Content type: Review Published on:

  26. Screening and early diagnosis of oral squamous cell carcinoma (OSCC) are directly associated with increased survival rate and improved prognosis. Noninvasive diagnostic tools have been implemented in the early...

    Authors: Alaa Elnaggar, Gihane Madkour, Neveen Tahoun, Ayman Amin and Fat’heya M. Zahran
    Citation: Journal of the Egyptian National Cancer Institute 2023 35:31
    Content type: Research Published on:

  27. Small cell osteosarcoma is an extremely rare histopathological variant of conventional osteosarcoma. Due to nonspecific symptoms, most osteosarcomas of the jaws are misdiagnosed as periapical abscesses and mis...

    Authors: Hatem Wael Amer, Hana’a Hezam Algadi and Shyma’a Ahmed Hamza
    Citation: Journal of the Egyptian National Cancer Institute 2023 35:30
    Content type: Case Reports Published on:

  28. Hodgkin lymphoma (HL) is a highly curable malignant tumor. Risk-adapted treatment for children with HL aims to maximize survival while minimizing toxicity. The purpose of this study is to evaluate the outcome ...

    Authors: Nesreen Ali, Mohamed Mansour, Ehab Khalil and Emad Ebeid
    Citation: Journal of the Egyptian National Cancer Institute 2023 35:29
    Content type: Research Published on:

  29. Breast cancer is the most common tumor among women throughout the world. Diagnosis and treatment of breast cancer are associated with stress and depression. Self-efficacy is one of the most important personal ...

    Authors: Azza El-Amir, Eman M. El-Baiomy, Noha A. Sabry, Loay Kassem, Margaret A. Chesney and Kenneth A. Wallston
    Citation: Journal of the Egyptian National Cancer Institute 2023 35:28
    Content type: Research Published on:

  30. Hypoxia arises due to insufficient oxygen delivery to rapidly proliferating tumour cells that outpace the available blood supply. It is a characteristic feature of most solid tumour microenvironments and plays...

    Authors: Shinjini Bandopadhyay and Somi Patranabis
    Citation: Journal of the Egyptian National Cancer Institute 2023 35:27
    Content type: Review Published on:

  31. Both S100A4 and Glypican-3 have been known to be engaged in HCC development and progression. This study aimed to evaluate both S100A4 and GPC3 expression in HCC tissues as a prognostic markers.

    Authors: Mahmoud El-Bendary, Khaled Farid, Mohammad Arafa, Wagdi Elkashef, Talaat Abdullah and Ahmed El-Mesery
    Citation: Journal of the Egyptian National Cancer Institute 2023 35:26
    Content type: Research Published on:

  32. The huge number of detected somatic KIT mutations highlights the necessity of in silico analyses that are almost absent in the relevant medical literature. The aim of this study is to report the mutation spectrum...

    Authors: Nour Pharaon, Wafa Habbal and Fawza Monem
    Citation: Journal of the Egyptian National Cancer Institute 2023 35:25
    Content type: Research Published on:

  33. Breast cancer is the most common tumor among females globally. Its prevalence is growing around the world, and it is alleged to be the leading cause of cancer death. Approved anti-breast cancer drugs display s...

    Authors: Sagiru Hamza Abdullahi, Adamu Uzairu, Gideon Adamu Shallangwa, Sani Uba and Abdullahi Bello Umar
    Citation: Journal of the Egyptian National Cancer Institute 2023 35:24
    Content type: Research Published on:

  34. Immunohistochemical expression of P53 protein is so closely related to status of mutation of P53 gene which is tightly linked with pathogenesis of nephroblastoma or Wilms tumor. This study aims to determine th...

    Authors: Emmanuel D. Morgan, James J. Yahaya, Advera I. Ngaiza, Emmanuel Othieno and Okwi A. Livex
    Citation: Journal of the Egyptian National Cancer Institute 2023 35:23
    Content type: Research Published on:

  35. Glioblastoma multiforme (GBM) is one of the most malignant types of central nervous system tumors. GBM patients usually have a poor prognosis. Identification of genes associated with the progression of the dis...

    Authors: Seema Sandeep Redekar, Satishkumar L. Varma and Atanu Bhattacharjee
    Citation: Journal of the Egyptian National Cancer Institute 2023 35:22
    Content type: Research Published on:

  36. The purpose of this study was to assess the usefulness of fluorodeoxyglucose positron emission tomography (18F-FDG PET)-computed tomography (CT) scan for staging urinary bladder cancer. The study also sought to d...

    Authors: Mohammed Shahait, Ramiz Abu-Hijlih, Ala’a Farkouh, Shahed Obeidat, Samer Salah, Ahmed Saad Abdlkadir and Akram Al-Ibraheem
    Citation: Journal of the Egyptian National Cancer Institute 2023 35:21
    Content type: Research Published on:

  37. In the Ugandan setting, investigation for PHNM with CT uses a protocol with both unenhanced and contrast enhanced procedures hence doubling the ionizing radiation exposure. The purpose of this study was to det...

    Authors: Alex Mwesigwa Mugisha, Zeridah Muyinda, Joyce Balagadde Kambugu, Denise Apolot, Elizabeth Atugonza, Anneth Teu and Aloysius Gonzaga Mubuuke
    Citation: Journal of the Egyptian National Cancer Institute 2023 35:20
    Content type: Research Published on:

  39. Acute lymphoblastic leukemia (ALL) is a malignancy that leads to altered blast cell proliferation, survival, and maturation and eventually to the lethal accumulation of leukemic cells. Recently, dysregulated e...

    Authors: Mahdiyar Iravani Saadi, Mohsen Nikandish, Zahra Ghahramani, Fatemeh Mardani Valandani, Maryam Ahmadyan, Fakhroddin Hosseini, Zahra Rahimian, Heeva Jalali, Fataneh Tavasolian, Ehsan Nabi Abdolyousefi, Nadiya Kheradmand and Mani Ramzi
    Citation: Journal of the Egyptian National Cancer Institute 2023 35:18
    Content type: Research Published on:

  40. T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive malignancy with few accepted prognostic factors that limit the efficiency of therapy. The aim of the current study was to assess the clinical and la...

    Authors: Mona S. El Ashry, Enas Radwan, Mona S. Abdellateif, Omar Arafah and Naglaa M. Hassan
    Citation: Journal of the Egyptian National Cancer Institute 2023 35:17
    Content type: Research Published on:

  41. Metaplastic breast cancer (MetBC) still represents a conundrum owing to its peculiar histogenesis and molecular drivers that render it extremely resistant to standard chemotherapy with ultimate dismal survival.

    Authors: Yahia Ismail, Amr Kamal, Rasha Allam and Al-Shimaa Zakaria
    Citation: Journal of the Egyptian National Cancer Institute 2023 35:16
    Content type: Research Published on:

  42. A malignancy of the endocrine system, one of the most common types, is thyroid cancer. It is proven that children who receive radiation treatment for leukemia or lymphoma are at a heightened risk of thyroid ca...

    Authors: Iyshwarya Bhaskar Kalarani, Ganesan Sivamani and Ramakrishnan Veerabathiran
    Citation: Journal of the Egyptian National Cancer Institute 2023 35:15
    Content type: Review Published on:

  43. Breast cancer is the most common female cancer worldwide. Its diagnosis and prognosis remain scanty, imprecise, and poorly documented. Previous studies have indicated that some genetic mutational signatures ar...

    Authors: Patrick Odhiambo, Harrison Okello, Annette Wakaanya, Clabe Wekesa and Patrick Okoth
    Citation: Journal of the Egyptian National Cancer Institute 2023 35:14
    Content type: Research Published on:

  44. The prognostic value of the level of programmed death ligand 1 (PD-L1) expression in non-Hodgkin lymphoma (NHL) is still debatable. This study examined the effect of the level of PD-L1 expression on the clinic...

    Authors: Eman Mohamad Ibrahim, Sherine Refat, Shaimaa El-Ashwah, Maryan Waheeb Fahmi and Afaf Taha Ibrahiem
    Citation: Journal of the Egyptian National Cancer Institute 2023 35:12
    Content type: Research Published on:

  45. Neoadjuvant chemotherapy (NAC) before radical cystectomy (RC) became the standard of care for muscle-invasive bladder cancer (MIBC) in the last few years. We aimed to evaluate the radiological, pathological re...

    Authors: Ibrahim Abdelrahman, Hatem Aboulkassem, Abdallah Elazab, Ahmed Younis Abdallah, Yahia Ismail and Mohammad Taher
    Citation: Journal of the Egyptian National Cancer Institute 2023 35:13
    Content type: Research Published on:

  46. This study was performed to investigate the expression of different biomarkers in patients with hepatocellular carcinoma and its connection with detective biomarkers. To achieve this objective, seventy subject...

    Authors: Ahmed Daif, Mahmood A. Al-Azzawi, Moustafa A. Sakr, Hisham A. Ismail and Mahmoud Gadallah
    Citation: Journal of the Egyptian National Cancer Institute 2023 35:11
    Content type: Research Published on:

  48. Health-related quality of life has emerged as a significant component in pediatric oncology research during the last several decades. Measures of health-related quality of life provide a thorough assessment of...

    Authors: Mai Sabry Saleh, Asmaa Mahmoud Mohammed, Dina Bassiouni, Hend Helmy Mostafa and Zeinab Mohammed Monir
    Citation: Journal of the Egyptian National Cancer Institute 2023 35:9
    Content type: Research Published on:

  49. Gastric cancer is a dominant source of cancer-related death around the globe and a serious threat to human health. However, there are very few practical diagnostic approaches and biomarkers for the treatment o...

    Authors: Mousa Fadaei, Maryam Kohansal, Omidreza Akbarpour, Mahsa Sami and Ali Ghanbariasad
    Citation: Journal of the Egyptian National Cancer Institute 2023 35:8
    Content type: Research Published on:

  50. Driver molecular aberrations, such as epidermal growth factor receptor (EGFR) mutation and anaplastic lymphoma kinase (ALK) gene rearrangement, play an important role in the oncogenesis and progression of non-squ...

    Authors: Mohamed Said Ismail, Loay Kassem, Ahmed Al-Husseiny Ali, Fatma Elzahraa Ahmed, Mohamed Shalaby and Sally Magdy
    Citation: Journal of the Egyptian National Cancer Institute 2023 35:7
    Content type: Research Published on:
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  • ISSN: 2589-0409 (electronic)